Additionally, the set will introduce new cards that will change the metagame such as Emma Frost, Madripoor, Marvel's First Family, Mimic and Sentinel Mark III; and Evasion - which allows characters to have more tactical attacking and defending choices during combat.

In the Marvel TCG, each player begins the game with 50 endurance points, which represent the overall strength of that player's team of heroes. The object of the game is to reduce your opponent's endurance to zero.